From Bots to Docs: Harnessing AI in the Undergraduate Med School Journey. Talk given July 17, 2023, Umeds section of Association of Pathology Chairs.

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Robbins is wrong (or at least misleading).

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In my previous post, I suggested a central dogma for students of pathology. After injury, a physiologic response maintains homeostasis without loss of function while a pathologic response leads to reduced function, even if a new homeostatic set point is reached.  With that in mind, let us turn to the first figure in the textbook that most of us consider the “standard of care” for pre-clinical instruction, Robbin’s textbook of pathology. The first figure is an opportunity for pathology to state the central dogma of the field.  Unfortunately, this figure is terrible.  The figure lists various names such as cell injury and death, homeostasis and adaption, reversible and irreversible injury. The relationship of these to each other seems arbitrary, ignoring definitions or time course. At most, one learns that some how a cell at rest maintains homeostasis, but that the cell can be injured, that sometimes this injury is mild and can be repaired, sometimes there is something call...
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