From Bots to Docs: Harnessing AI in the Undergraduate Med School Journey. Talk given July 17, 2023, Umeds section of Association of Pathology Chairs.

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What is the central dogma of pathology?

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 Pathology has been a central pillar of allopathic medicine since the dawn of scientific medicine. However, with respect to medical education, pathology no longer is a stand alone course.  Pathologists must therefore make the underlying message of pathology as clear as possible or get lost in the firehose of information that medical students are subject to from their first day of classes. The central dogma of molecular biology as enunciated by Crick in 1958 is that information required to run an organism flows from DNA to RNA to protein. It represents the entire field as a flow of information, rather than as a series of molecular interactions. For the student, this is a very attractive proposition, rather than considering molecular biology as a series of endless organic chemistry reactions.  Pathology needs something similar or will forever be viewed at random (uninterpretable) histologic images. I was taught that “all disease occurs as a response to injury”. Unfortunatel...
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