My shot...at revising ILD histopathology criteria
I had to do it. My Yale ancestors created UIP/DIP and the like (although they got those largely wrong, see my previous blog posts). So it is now my turn. While Tom Colby long ago relegated the wedge biopsy from gold to a silver standard, such biopsies are still considered potentially helpful. But how do we assess even a silver standard? A few years ago, I felt frustrated that the biopsies I was looking at seemed difficult to classify and wanted additional input. I recruited an international group of pathologists with interest/expertise in ILD to review a series of cases using both fixed and whole slide images to see if we could improve our criteria. We have recently published this work (no paywall). https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-021-01522-6 For the truly curious, all the images used in this study are available online. http://pathmodule.org/PathCamp/virtualslideshare/ The approach we took paralleled that taken by Carol Farver (a mem...